Kambo is applied to the body via small burn marks made to the skin, often called Kambo dots or gates. The medicine initially elicits a wide variety of “cleansing and detoxing” symptoms, which often include some amount of purging (vomiting), as well as sweating, crying, or physical tremoring. These release valves, it is said, are the process by which Kambo elicits its mind/body healing effects through a massive discharge of accumulated tension, stress, and toxins from the physical body. Scientifically, you could say that Kambo is very much a nervous system oriented medicine, effectively down-regulating the body and putting one into a more parasympathetic state of being, helping the individual to recalibrate and find homeostasis again. Metaphysically, the indigenous believe that Kambo opens up ones energy field by removing Panema, or bad luck, from a persons field, thereby realigning their spirit with the positive energy of nature and the cosmos more and more overtime.